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新辅助化疗对进展期胃癌手术风险的研究
引用本文:王公平,张斌. 新辅助化疗对进展期胃癌手术风险的研究[J]. 河南外科学杂志, 2009, 15(5): 2-4
作者姓名:王公平  张斌
作者单位:河南科技大学第一附属医院肿瘤科,洛阳,471003;河南省肿瘤医院普外科
摘    要:目的评估新辅助化疗对进展期胃癌手术风险的影响。方法全组27例患者,均经胃镜活检确诊为腺癌,采用FOLFOX-6方案术前化疗2个周期。结果有效率为50.0%(13/27),手术风险无增加,主要不良反应为胃肠道反应,骨髓抑制和周围神经毒性。结论FOLFOX-6方案作为进展期胃癌新辅助化疗方案安全有效,值得临床推广应用。

关 键 词:进展期胃癌  新辅助化疗  手术风险

Study on the operational risk of new adjuvant chemotherapy in treating advanced gastric cancer
WANG Gongping,ZHANG Bin. Study on the operational risk of new adjuvant chemotherapy in treating advanced gastric cancer[J]. Henan JOurnal of Surgery, 2009, 15(5): 2-4
Authors:WANG Gongping  ZHANG Bin
Affiliation:WANG Gong-ping1,ZHANG Bin2.1.Department of Oncology,Henan University of Science , Technology,Luoyang 471003,China,2.Department of General Surgery,Henan Provincial Tumor Hospital
Abstract:Objective To evaluate the effect of new adjuvant chemotherapy on advanced gastric cancer.Methods Twenty-seven patients pathologically diagnosed as gastric adenocarcinoma were chosen to be treated two cycles with FOLFOX-6 regimen before operation.Results The effective rate was 50 percent.Operative risk was not added and the major toxicity reaction were gastrointestinal reaction,peripheral neurotoxicity and myelosuppression.Conclusion As the preoperative treatment method of advanced gastric cancer,FOLFOX-6 re...
Keywords:Advanced cancer  New adjuvant chemotherapy  Operative risk  
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