Pediatric HIV/AIDS and the skin: an update

In 2005 there were 2.1 million children under the age of 15 years living with HIV in sub-Saharan Africa. As in the adult pandemic, attendant skin disease is prevalent in children. This article provides an update of pediatric HIV/AIDS and its cutaneous manifestations from four main aspects: epidemiology, skin disease as an indicator of immune status, immune reconstitution inflammatory syndrome, and the impact of antiretroviral agents on skin disease.