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Gas chromatographic determination of residual ethylene oxide in the endotracheal tube
Authors:S Todoroki  S Haseba  M Kanairo  T Tanaka  Y Gotoh
Affiliation:Department of Anesthesiology, University of Nagasaki School of Medicine.
Abstract:An accurate and simplified method has been developed for determination of residual ethylene oxide (EO) in the endotracheal tube using gas chromatography with a head space sampler. The endotracheal tube made of polyvinyl chloride was sterilized with EO and aerated. Residual EO after aeration was 6630 +/- 1915 ppm (mean +/- SD). It decreased to 72 +/- 46 ppm on 7th day. The endotracheal tube should be left unused for more than 7 days after sterilization and aeration. The safety level of residual EO in the endotracheal tube by U.S.FDA regulation is less than 250 ppm. The concentration of residual EO should be lower than 250 ppm, if this rule is observed.
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