| 胰高血糖素样肽1对脂肪细胞作用的研究进展 |
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| 引用本文： | 鞠现霞,崔琴.胰高血糖素样肽1对脂肪细胞作用的研究进展[J].医学综述,2010,16(18). |
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| 作者姓名： | 鞠现霞 崔琴 |
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| 作者单位： | 南京医科大学第一附属医院内分泌科,南京,210029 |
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| 摘 要： | 胰高血糖素样肽1(GLP-1)在体内可发挥多种生物学作用,在应用于2型糖尿病及肥胖的防治中,除作用于胰岛β细胞发挥一系列生物学作用外,GLP-1对脂肪细胞的功能也有调节作用。具体体现在GLP-1对脂肪细胞糖代谢、脂质代谢及脂肪细胞因子表达的影响。GLP-1对脂肪细胞的这些作用可更全面地解释其治疗2型糖尿病的作用机制。
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| 关 键 词： | 胰高血糖素样肽1 脂肪细胞 2型糖尿病 肥胖 |
Progress of Adipocytes Effects by Glucagon-like Peptide 1 |
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| JU Xian-xia,CUI Qin.Progress of Adipocytes Effects by Glucagon-like Peptide 1[J].Medical Recapitulate,2010,16(18). |
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| Authors: | JU Xian-xia CUI Qin |
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| Abstract: | Glucagon-like peptide 1(GLP-1)can play a variety of biological effects in vivo.In addition to acting on pancreatic β cells in type 2 diabetes and obesity prevention,GLP-1 may regulate the function of adipocytes.In particularly the effects of GLP-1 on glucose metabolism,lipid metabolism and adipocytokine expression of adipocytes.These effects of GLP-1 on adipocytes will contribute to explaining the mechanism of action of GLP-1 for the therapy of type 2 diabetes. |
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| Keywords: | Glucagon-like peptide 1 Adipocyte Type 2 diabetes Obesity |
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