Secoiridoid glucosides with free radical scavenging activity from the leaves of Syringa dilatata |
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| Authors: | Oh Hyuncheol Ko Eun-Kyoung Kim Do-Hoon Jang Kyu-Kwan Park Sung-Eun Lee Ho-Sub Kim Youn-Chul |
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| Affiliation: | Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Korea. |
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| Abstract: | Activity-guided fractionation of the EtOAc and MeOH extract of the leaves of Syringa dilatata NAKAI furnished one free radical scavenger, the secoiridoid glucoside oleuropein together with ligstroside and an iridoid glucoside, syringopicroside. Oleuropein interacted with the stable free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), and showed an IC(50) value of 40.4 microM. L-Ascorbic acid as a positive control showed an IC(50) value of 50.3 microM. |
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| Keywords: | Syringa dilatata free radical scavenger secoiridoid |
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