1型糖尿病胰岛素泵治疗临床观察

目的观察1型糖尿病患儿早期行胰岛素泵持续胰岛素（INS）皮下输注的疗效。方法将1型糖尿病患儿分为两组进行胰岛素强化治疗，胰岛素泵持续皮下胰岛素输注（csII）组17例，多次皮下胰岛素注射（MsII）组15例。结果两组达到目标血糖时，csII组所需的治疗时间以及低血糖发生率明显比MsII组减少，且采用胰岛素泵治疗的患儿生活质量优于常规注射治疗患儿（P均〈0．05）。结论csII比MsII可以更快、更有效地控制高血糖，降低低血糖的发生率，减少糖尿病并发症发生，提高生活质量。

Clinical observation of insulin pump treatment of type 1 diabetes mellitus

Objective To observe the effect of early continuous insulin pump insulin （INS） subcutaneous infusion on type 1 diabetes mellitus （T1DM） in children. Methods Type 1 diabetes mellitus patients were divided into two groups for insulin therapy, insulin pump continuous subcutaneous insulin infusion （csI I） 15 cases, multiple subcutaneous insulin injections （MsI I） group of 17 cases. Results When the two groups achieve the target blood glucose results, csI I group required treatment time, and low blood glucose was significantly less than the MSI I （ P all 〈 0.05 ）. And the use of insulin pump therapy in children with quality of life is superior to conventional injection therapy in children （P all 〈 0.05 ）. Conclusions CsI I faster than MsI I can more effectively control high blood glucose, reduce the incidence of low blood glucose, and can improve the quality of life.