| 替罗非班对急性心肌梗死病人PCI术后可溶性CD40配体影响的观察 |
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| 引用本文： | 胡永寸,刘慧. 替罗非班对急性心肌梗死病人PCI术后可溶性CD40配体影响的观察[J]. 中原医刊, 2011, 0(1): 68-69,71 |
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| 作者姓名： | 胡永寸 刘慧 |
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| 作者单位： | 河南省安阳地区医院心内科,455000 |
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| 摘 要： | 目的观察急性ST段抬高的心肌梗死病人在接受雷帕霉素洗脱支架植入术后应用替罗非班治疗对血浆可溶性CD40配体（SCD40L）的影响。方法将70例接受雷帕霉素洗脱支架治疗的ST段抬高性心肌梗死病人分为接受替罗非班治疗组（35例）和常规治疗组（35例），用ELISA法测定术后即刻、术后2h、术后48h血清中SCD40L的水平。结果替罗非班治疗组中血清SCD40L水平明显低于对照组（P〈0．05）。结论接受雷帕霉素洗脱古契艚入治井酌鱼牲ST船抬高性心肌柏并．病人术后棒旁替节非斑治疗后SCD40L水平明显下降．
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| 关 键 词： | 急性ST段抬高性心肌梗死 替罗非班 雷帕霉素 可溶性CD40配体 |
Effect of tirofiban to the SCD40L in acute myocardial infarction after PCI |
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| HU Yong-cun,LIU Hui. Effect of tirofiban to the SCD40L in acute myocardial infarction after PCI[J]. Central Plains Medical Journal, 2011, 0(1): 68-69,71 |
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| Authors: | HU Yong-cun LIU Hui |
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| Affiliation: | .( Department of Cardiology, Anyang District Hospital, Anyang 455000, China) |
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| Abstract: | Objective To evaluate the effect of tirofiban on the blood plasma soluble CD40 ligand （SCD40L） in patients with acute ST- elevated myocardial infarction（STEMI） after PCI. Methods Seventy patients with STEMI who underwent PCI were randomly divided into two groups：the tirofiban ＋ PCI group（ n = 35） and PCI without tirofiban treatment group（n = 35）. SCD40L were tested by ELISA at three time - point ： just afrer PCI, 2 hours and 48 hours. Results The Level of SCD40L was decreased in tirofiban group than in the control group obviously （ P 〈 0.05 ）. Conclusions The level of SCD40L decreases obviously in patients with STEMI after PCI treated by tirofiban. |
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| Keywords: | Acute ST - elevated myocardial infarction Tirofiban Rapamycin SCD40L |
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