早期静脉营养在早产低出生体重儿中的应用

目的：对比研究两种静脉营养方法对早产低出生体重儿的疗效。方法：按静脉营养方式不同，将不能耐受全胃肠道喂养的早产低出生体重儿随机分为两组，每组各30例，实验组采用早期静脉营养（early parenteral nutrition，EPN），对照组采用传统静脉营养（traditional parenteral nutrition，TPN），比较两组患儿2周内体重增长情况，过渡到全胃肠道喂养的时间，静脉营养相关并发症。结果：实验组2周内体重增长均高于对照组（P〈0.01）；两组过渡到全胃肠道喂养时间差异无统计学意义（P〉0.05）；两组静脉营养相关并发症发生率差异无统计学意义（P〉0.05）。结论：早产儿低出生体重儿采用早期静脉营养比传统静脉营养体重增长快，可以避免早期营养不良的发生，对过渡到全胃肠道喂养的时间没有影响，不会增加静脉营养相关并发症。

The application of early vein nourishment in the premature infants

Objective:This study aimed to compare the effects of the two methods on nutrition states and the incidence of complication associated with parenteral nutrition(PN).To investigate the effect of early parenteral nutrition(EPN)on the weight increase of premature infants.Methods:Total 60 survival premature infants with low birth weight or very low birth weight in our hospital were divided into two groups randomly,with 30 infants in each group.The infants in the trial group were given early PN(EPN)to improve weight growing,and those in the control group given traditional PN(TPN).The body weight,the time taken to attain of full enteral nutrition,and the incidence of complication were recorded daily.All the data were analyzed statistically.Results:Daily weight gain in the first two weeks in the early PN group were much greater than those of the conventional PN group(P<0.01);The time taken for the two groups to go on full enteral nutrition was similar;No significant difference was observed in the incidence of complication between the two groups.Conclusion:The body weight gain were found to be greater in the early PN group than in the conventional PN group in low birth weight premature infants.The incidence of complication associated with PN and the initiation of gastrointestinal function are unrelated to the PN administration method.