原发性肝癌介入治疗后疗效影响因素的分析

目的探讨原发性肝癌介入治疗后影响预后的各种因素及其对患者生存期的影响。方法258例原发性肝癌患者接受介入治疗,对临床各种资料以及患者存活情况进行分析研究。结果Cox回归多因素分析显示原发性肝癌介入治疗的预后与患者肝功能分级、治疗方法及碘油沉积情况密切相关。单因素分析显示不同病理类型、不同肝功能分级、门脉内有无瘤栓、不同碘油沉积情况下及不同治疗方案累积生存率不同,绝大多数之间有统计学显著性差异。结论Cox回归模型可以较全面的综合分析对原发性肝癌治疗效果有显著意义的因素。

Analysis of the Factors of Influence on the Therapeutic Effect of Primary Hepatic Carcinoma after Interventional Therapy

Objective To evaluate the factors of influence on the prognosis and survival rate in patients of primary hepatic cellular carcinoma(HCC) after interventional therapy.Methods 258 cases of HCC were treated with interventional therapy,the data of these cases and the survival rate were analysed.Results The prognosis in patients with HCC was relation to the hepatic function,therapeutic methods and accumulation of iodized oil by analysis of Cox Regression.The cumulative survival rate was different in HCC with different pathological type,different grade of hepatic function,with or without tumor embolus in portal vein,different cumulation of iodized oil and different therapetic methods,there was significance in statistics between most of them.Conclusion Cox Regression model can be used to analyse synthetically the factors that significantly affected the survival period in the patients with HCC.