| 人参茎叶皂甙对大鼠脑内γ-氨基丁酸的影响 |
| |
| 引用本文： | 宗瑞义,陈声武.人参茎叶皂甙对大鼠脑内γ-氨基丁酸的影响[J].吉林大学学报(医学版),1987(3). |
| |
| 作者姓名： | 宗瑞义 陈声武 |
| |
| 作者单位： | 白求恩医科大学药理教研室
(宗瑞义)，白求恩医科大学药理教研室(陈声武) |
| |
| 摘 要： | 本文报告了人参茎叶皂甙、二醇组皂甙及三醇组皂甙对大鼠脑内r-氨基丁酸(以下简称GABA)正常水平无明显改变,而预先应用大剂量的异烟胼后,再服用人参茎叶皂甙、二醇组皂甙及三醇组皂甙,则前二者皆能非常明显的升高由异烟肼所引起的脑内GABA水平的降低。
|
| 关 键 词： | γ-氨基丁酸 异烟肼 人参茎叶皂甙 二醇组皂甙 三醇组皂甙 |
Influence of ginsenosides on γ-aminobutyric acid level in brain of rats |
| |
| Zong Ruiyi and Chen Shengwu.Influence of ginsenosides on γ-aminobutyric acid level in brain of rats[J].Journal of Jilin University: Med Ed,1987(3). |
| |
| Authors: | Zong Ruiyi and Chen Shengwu |
| |
| Institution: | Zong Ruiyi and Chen Shengwu |
| |
| Abstract: | The influence of ginsenosides, including the total ginsenosides as well as panaxadiol and panaxatriol, on CABA content in the brain was experimentally studied. Administration of these compounds to normal rats did not result in any changes in the content of GABA, but when they were administered to rats pretrated with isoniazide 20 min before, the total ginsenosides and panaxadiol, but not panaxatriol, caused a significant increase in the content of GABA. These data indicate that the total ginsenosides and panaxadiol have certain inhibitory effects on the central nervous system and some influence on GABA system. However, the exact mechanism awaits further study. |
| |
| Keywords: | Ginseng Total ginsenosides Panaxadiol Panaxatriol GABA Neural inhibition |
| 本文献已被 CNKI 等数据库收录！ |
