耐多药肺结核患者肾上腺皮质水平的临床研究

目的　探讨耐多药肺结核患者肾上腺皮质水平的变化规律。方法 采用放射免疫分析法对56例耐多药肺结核患者进行血清皮质醇含量测定,并与无耐药肺结核、正常健康人进行对比。结果 耐多药肺结核患者的皮质醇含量分别为842±168(8AM)、624±62(4PM),均明显高于非耐药肺结核组和正常组。结论 耐多药肺结核患者肾上腺皮质功能较正常人明显增加,且皮质醇分泌仍具有正常节律性。

Clinical research of cortiadrenal function in patients with multi-drug resistant pulmonary tuberculosis

Objective To study the change of cortiadrenal function in patient with multi-drug resistant pulmonary tuberculosis.Methods The serum cortisols of 56 patients with multi-drug resistant pulmonary tuberculosis were measured by radiation immunity analysis (RIA),and compared with that of the group of non-drug resistant pulmonary tuberculosis and the normal control group.Results The serum cortisol level of the studied group was significantly higher than the others,there were 842±168(8AM) and 624±62(4PM) positive.Conclusion The cortiadrenal function of the studied group was stronger obviously than normal,but the rhythm of their cortisol excretion was normal.