血清腹水白蛋白梯度在腹水临床诊断中的价值

目的比较血清腹水白蛋白梯度与渗出液／漏出液对腹水鉴别诊断的准确性。方法选择诊断明确腹水病例53例，将其分为门脉高压组（A组，n=30）及非门脉高压组（B组，n=23）。比较传统的渗漏出液的分类方法及以血清腹水白蛋白梯度方法对腹水病因诊断的准确率。结果血清腹水白蛋白梯度的诊断准确性为94．34％，敏感性96．67％，特异性为91．31％，高于传统的渗漏出液指标的准确率。结论将腹水依据血清腹水白蛋白梯度判定为门脉高压相关性及非门脉高压相关性，在临床上将具有更强的实用性及更广泛的应用价值。

Value of serum ascites albumin gradient in clinical diagnosis of ascites

Objective To compare the serum-aseities albumin gradient(SAAG)and exudate-transudate concept in the differential diagnosis of ascites.Methods A total of 53 paired sera and ascitic fluid data were retrospectively collected from patients with well-characterized causes of ascites.30 patients with aseites were portal-hypertension-related and 23 patients were not related to portal hypertension.Diagnostic accuracy of the serum ascites albumin gradient and previously proposed markers for the separation of ascites into transudate and exudate were compared.Results The serum-ascites albumin gradient had a diagnostic accuracy of 94.34%,superior to that of the total ascitic fluid protein(84.91% ).Conclusion Serum ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites.