人体双髋骨密度分布规律研究

目的 探索人体双髋骨密度(bone mineral density,BMD)的分布规律,为选择髋部感兴趣区提供依据.方法 用GE Lunar Prodigy型双能X线骨密度仪(dual-energy X-ray absorptiometry,DXA)测量受检者双髋BMD,感兴趣区选择股骨颈和全髋部.结果 共检测301例,其中男性135例,左右侧股骨颈BMD差值为(0.004±0.048)g/cm~2,左右侧全髋部BMD差值为(0.006±0.042)g/cm~2,差异均无统计学意义;高低侧股骨颈BMD差值为(0.038±0.029)g/cm~2[95%CI(0.034,0.043)],高低侧全髋部BMD差值为(0.035±0.025)g/cm~2[95%CI(0.030,0.039)].女性166例,左右侧股骨颈BMD差值为(0.006±0.040)g/cm~2,左右侧全髋部BMD差值为(0.003±0.036)g/cm~2,差异均无统计学意义;高低侧股骨颈BMD差值为(0.032±0.025)g/cm~2[95%CI(0.028,0.036)],高低侧全髋部BMD差值为(0.030±0.021)g/cm~2[95%CI(0.027,0.033)].无论男性还是女性,髋部股骨颈BMD与全髋部BMD呈正相关.结论 人体左右侧髋部感兴趣区BMD总体分布基本一致,但个体髋部存在优势侧与非优势侧,建议测量双侧髋部BMD,并报告较低的一侧.

Distribution of bone mineral density in dual femur of human being

Objective Research for dual femur bone mineral density (BMD) distribution of human being, in order to provide an evidence of how to choose the region of interest. Methods Dual femur BMD of subjects were detected by double-energy X-ray absorptiometry (GE Lunar Prodigy). Femur neck and the total hip were selected as region of interest. Results 301 subjects were detected, 135 were male, whose BMD differences of left and right side of femur neck were (0.004±0.048)g/cm~2, while those of the total hip were (0.006±0.042)g/cm~2, not statistically significant. The differences between the higher density and the lower density of femur neck were (0.038±0.029)g/cm~2[95%CI(0.034,0.043)], while those of the total hip were (0.035±0.025)g/cm~2[95%CI(0.030,0.039)]. 166 were female, whose BMD differences of left and right side of femur neck were (0.006±0.040)g/cm~2, while those of the total hip were (0.003±0.036)g/cm~2, not statistically significant. The differences between the higher density and the lower density of femur neck were (0.032±0.025)g/cm~2[95%CI(0.028,0.036)], while those of the total hip were (0.030±0.021)g/cm~2[95%CI(0.027,0.033)]. In both men and women, the BMD of the femur neck and the total hip have a positive correlation. Conclusion BMD distributions of human being of the region of interest in both left and right hip is almost conformity, but because of the ascendant side exist, detecting both side of hip is suggested and the lower side should be reported as the BMD.