18F]fluorodeoxyglucose positron emission tomography in the diagnosis of cancer in patients with paraneoplastic neurological syndrome and anti-Hu antibodies |
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| Authors: | Antoine J C Cinotti L Tilikete C Bouhour F Camdessanché J P Confavreux C Vighetto A Renault-Mannel V Michel D Honnorat J |
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| Affiliation: | Service de Neurologie, H?pital de Bellevue, Faculté de Médecine Jacques Lisfranc, Saint-Etienne, France. |
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| Abstract: | The diagnosis of cancer is often difficult in patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Fluorodeoxyglucose 18 positron emission tomography scanning is a highly sensitive and specific method to detect lung tumors. We investigated 15 patients with paraneoplastic neurological syndrome and anti-Hu antibodies. Radiological methods led to the diagnosis of cancer in 12 patients, and test results were negative in 3. Whole-body [18F]fluorodeoxyglucose positron emission tomography showed abnormal uptake in the mediastinum in these 3 patients in accordance with the expected location of the malignancy. |
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