| 一平苏对维持性血透患者心血管保护作用的临床观察 |
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| 引用本文： | 刘沁,叶朝阳,方平,高文武.一平苏对维持性血透患者心血管保护作用的临床观察[J].中华高血压杂志,2001,9(2):114-116. |
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| 作者姓名： | 刘沁 叶朝阳 方平 高文武 |
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| 作者单位： | 1. 第二军医大学长征医院, 肾内科
2. 第二军医大学长征医院, B超室 |
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| 摘 要： | 观察一平苏对维持血透患者的心血管保护作用。方法30例有高血压和左室肥厚并维持血透的患者随机分为两组，A组20例用一平苏2.5mg～5mg/d,B组给予不会影响左室重构的其它药作为对照。6个月后心脏多普勒超声检查左室重构及功能的情况。结果两组虽均有明显降压，但一平苏组治疗后LVDd，IVS，LVPWD和LVMI均有统计学意义的下降，EF和E/A均明显升高。结论一平苏不仅可安全有效地降压，还可逆转血透患者的左室肥厚及使左室舒张功能改善。
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| 关 键 词： | 血透 高血压 西拉普利 左室肥厚 左室功能 |
| 文章编号： | 1006-2866(2001)02-0114-02 |
| 修稿时间： | 2000年5月20日 |
Cardiovascular Protection Effect of Cilazapril in Hypertensive Hemodialysis Patients |
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| LIU Qin,YE ChaoYang,FANG Ping,GAO Wenwu.Cardiovascular Protection Effect of Cilazapril in Hypertensive Hemodialysis Patients[J].Chinese Journal of Hypertension,2001,9(2):114-116. |
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| Authors: | LIU Qin YE ChaoYang FANG Ping GAO Wenwu |
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| Abstract: | Objective:To investigate the cardiovascular protection effect of cilazapril in hemodialystic patients|(HD). Methods:Thirty HD with hypertension and left ventricular hypertrophy patients were randomly divided into two groups.Group A(n=20) cilazapril 2.5 mg～5 mg,group B(n=10) as control. After six mouths,the left ventricular mass and function were monitored by color Doppler cardiography. Results:BP was decreased in both group.LVDd,IVS,LVPWD and LVMI were decreased in cilazapril group. Conclusion:Cilazapril is not only effective and safe in treatment of hypertension,reversed the ventricular hypertrophy and improved the diastolic function in HD patients also. |
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| Keywords: | hemodialysis cilazapril hypertension Left ventricular hypertrophy and function |
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