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心元对狗血流动力学和心肌耗氧量的影响
引用本文:王正荣,肖静,郭惠玲,尹华虎,王红星,方国璋.心元对狗血流动力学和心肌耗氧量的影响[J].中国实验方剂学杂志,1995,1(2):22-25.
作者姓名:王正荣  肖静  郭惠玲  尹华虎  王红星  方国璋
作者单位:华西医科大学生物医学工程研究室,四川省医科院简阳动物中心,四川吉泰安药业有限公司
摘    要:本文对一种新的中药复方颗粒一心元进行了药效学研究。通过动物实验证明了心元有扩张冠状动脉,增加冠脉流量,减少心肌耗氧量等作用。因此,心元是一种能有效改善心血管机能和改善心肌能量代谢等作用的新药。

关 键 词:心元  血流动力学  心肌耗氧量

Effect of Xinyuan Granule on Dog's Hemodynamics and Myocardial Oxygen Consumption
Wang Zhengrong,Xiao jing,Guo Huiling,Yin Huahu,Wang Hongxing,Fang Guizhang.Effect of Xinyuan Granule on Dog''s Hemodynamics and Myocardial Oxygen Consumption[J].China Journal of Experimental Traditional Medical Formulae,1995,1(2):22-25.
Authors:Wang Zhengrong  Xiao jing  Guo Huiling  Yin Huahu  Wang Hongxing  Fang Guizhang
Institution:1.Biomedical Engineering Department,West China Yniversity of Medical Sciences;2.Jianyang Center of Experimental Animals,Sichuan Academy of medicalSciences;3.SiChuan Taian Pharmaceutic Co. Ltd
Abstract:The pharmacologic characteristics of Xinyuan granule,a Chinese drug formula,was investigated in this study.The data obtained in the animal experi- ments revealed that Xinyuan granule exhibited activities if dilating coronary artery,increasing blood flow in coronary artery and decreasing coronary circulatory resis- tance. In addition,the granule appeared to have hypotensive action and to lower my- ocardial oxygen consumption,Therefore,Xinyuan granule is a new medicine which can improve cardiovascular functions and myocardial energy metabolism.
Keywords:Xinyuan granule  Hemodynamics  Myocardial oxygen consumption
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