Breast cancer: genetics, risks, and strategies

Breast cancer is the most common cause of cancer among women, with 175,000 new cases diagnosed in 1999. The recent discovery of inherited mutations on the BRCA1 and BRCA2 genes and related research has increased our understanding of key risk factors. After identifying those who are at risk, health care providers must counsel women regarding appropriate prevention and early detection strategies. This article reviews the influence of genetics on breast cancer, identifies risk factors, discusses risk factor analysis, and suggests strategies for prevention and early detection of breast cancer.