急性脑梗死患者血清超敏C反应蛋白水平的相关研究

目的研究急性脑梗死（ACI）患者血清超敏C反应蛋白（hs-CRP）水平的变化及其与梗死体积及神经功能缺损程度的关系。方法测定147例急性脑梗死患者及80名健康对照者的血清hs-CRP含量，分析比较急性脑梗死患者在不同梗死体积、不同病情时血清hs-CRP含量的变化。结果急性脑梗死患者血清hs-CRP的水平明显高于对照组（p〈0．01），且血清hs-CRP含量越高，脑梗死灶越大，神经功能缺损程度越重，血清hs-CRP水平与病灶体积、病情轻重程度呈正相关（P〈0．01）。结论急性脑梗死与血清hs-CRP水平关系密切，hs-CRP不仅是脑梗死的危险因子，也可作为一个判断病情严重程度的客观指标。

Study on Serum High Sensitive C-reactive Protein Level in Patients with Acute Cerebral Infarction

Objective To study the changes of serum high sensitive C-reactive protein（hs-CRP） level in patients with acute cerebral infarction（ACl）, and its relationship with infarction volume as well as degree ofneurofunction impairment.Methods The content of serum hs-CRP in 147 patients with acute cerebral infarction and 80 normal controls was measured.The changes ofhs-CRP were compared in ACI patients with different infarction volume and pathogenetic condition.Results The levels of hs-CRP in ACI patients was significantly higher than that of the control group （P〈0.01）.The higher hs -CRP content, the larger volume of infarction and the more severe function impairment were.The levels of serum hs-CRP was positively correlative with the infarction volume and severity of the illness（P〈0.01）.Conclusion Relationship between the serum hs-CRP level and acute cerebral infarction is intimatel.The serum hs-CRP is a risk factor for acute cerebral infarction and an objective index to evaluate the severity.