| 具抗癌活性的鬼桕毒电子自旋标记物的生物学作用——研究Ⅰ.对细胞生长的抑制试验 |
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| 引用本文： | 张尔贤,欧阳春光,王燕鸣.具抗癌活性的鬼桕毒电子自旋标记物的生物学作用——研究Ⅰ.对细胞生长的抑制试验[J].中国生化药物杂志,1993(3). |
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| 作者姓名： | 张尔贤 欧阳春光 王燕鸣 |
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| 作者单位： | 汕头大学生物学系，汕头大学生物学系，汕头大学生物学系 |
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| 摘 要： | 用鬼桕毒自旋标记衍生物对子宫颈癌细胞(Hela)、乳地鼠肾传代细胞(BHK)和人胚肺成纤维细胞(KMB)进行了体外抑制试验,发现鬼桕毒自旋标记衍生物在用量为0.1mg时,对Hela、BHK细胞有较强的抑制作用。
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| 关 键 词： | 自旋标记衍生物 抗癌活性 鬼柏毒 细胞 抑制作用 |
Study on Biological Function of Spin-Labeled Anticancer Podophyllotoxin Derivatives——I . The Inhibition for the Growth of Cells |
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| Zhang Erxian,Ouyang Chunguang Wang Yanming.Study on Biological Function of Spin-Labeled Anticancer Podophyllotoxin Derivatives——I . The Inhibition for the Growth of Cells[J].Chinese Journal of Biochemical Pharmaceutics,1993(3). |
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| Authors: | Zhang Erxian Ouyang Chunguang Wang Yanming |
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| Institution: | Zhang Erxian,Ouyang Chunguang Wang Yanming
Department of Biology,Shantou University |
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| Abstract: | Hela KMB and BHK cells are found to be inhibited in vitro by spin labeled podophyllotoxin derivatives. By means of trypan blue staining, we have found that podophyllotoxin derivatives at a dose of 0. 1 mg bears considerable effect on cells of Hela and BHK. |
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| Keywords: | Spin labe led derivative Anticancer activity Podophyllotoxin Cell Inhibition |
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