痰热清佐治慢性阻塞性肺疾病并发呼吸衰竭42例

目的观察痰热清注射液辅助治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)并发呼吸衰竭的疗效。方法将82例COPD患者随机分为两组,治疗组42例,对照组40例,对照组仅予呼吸机及常规方案治疗,治疗组加用痰热清注射液静脉滴注,治疗后比较两组临床疗效、症状体征评分、血气分析指标及机械通气时间。结果治疗组总有效率显著高于对照组(90.47%vs 70.00%,P<0.01);治疗组在降低症状体征评分、使用呼吸机时间及改善血气分析指标方面优于对照组(P<0.01)。结论痰热清联合西医常规治疗在改善COPD患者咳嗽、咳痰、喘息症状,提高动脉氧分压,提高氧合指数,缩短上机时间方面具有较好疗效。

Therapeutic Efficacy of Tanreqing Injection as Adjuvant Therapy in Treatment of Chronic Obstructive Pulmonary Disease with Respiratory Failure: A Report of 42 Cases

Objective To observe the therapeutic efficacy of Tanreqing Injection as an adjuvant therapy in the treatment of chronic obstructive pulmonary disease (COPD) with respiratory failure.Methods Eighty two COPD patients were randomly divided into treatment group (n=42) and control group (n=40). The control group received respirator therapy and conventional treatment, while the treatment group was given Tanreqing Injection by intravenous drip in addition to respirator therapy and conventional treatment. The two groups were compared for response rate, symptom score, blood gas parameters, and mechanical ventilation duration after treatment. Results Compared with the control group, the treatment group showed a significantly higher overall response rate (90.47% vs 70.00%,P<0.01), as well as lower symptom score, shorter duration of mechanical ventilation, and better blood gas parameters (P<0.01). Conclusion Tanreqing Injection combined with conventional Western medicine treatment can improve such symptoms as cough, expectoration, and dyspnea, increase arterial partial pressure of oxygen and oxygenation index, and shorten the duration of mechanical ventilation in COPD patients.