| 老年收缩期高血压患者血清尿酸水平及氯沙坦钾的治疗作用 |
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| 引用本文： | 阴茜,杜心清,许朝祥. 老年收缩期高血压患者血清尿酸水平及氯沙坦钾的治疗作用[J]. 中国组织工程研究与临床康复, 2001, 5(9): 86-87 |
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| 作者姓名： | 阴茜 杜心清 许朝祥 |
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| 作者单位： | 福建医科大学附属第二医院, |
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| 摘 要： | 目的探讨老年收缩期高血压(ISH)患者血清尿酸水平的变化及氯沙坦钾的治疗作用。方法85例老年ISH患者和51例健康老年人血清尿酸水平的差异及老年ISH药物治疗(氯沙坦钾44例，苯那普利41例)8周后两组血压及血清尿酸水平变化的差异。结果老年ISH组血清尿酸水平显著高于正常对照组(P＜0.01)。经药物治疗8周后，两组降压效果无显著性差异，而两组治疗后血清尿酸水平，具有显著性差异(P＜0.01)。结论老年ISH患者血清尿酸水平显著升高，氯沙坦钾治疗ISH疗效肯定，且能有效地降低血清尿酸水平。
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| 关 键 词： | 高血压；尿酸；氯沙坦钾 |
| 修稿时间： | 2001-01-15 |
The serum uric acid level in systolic hypertension in the elderly and the effect of losartan potassium |
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| YIN Cheng-qian,DU Xinqing,XU Chao-xiang. The serum uric acid level in systolic hypertension in the elderly and the effect of losartan potassium[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2001, 5(9): 86-87 |
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| Authors: | YIN Cheng-qian DU Xinqing XU Chao-xiang |
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| Abstract: | Objective To investigate the serum uric acid level in isolated systolic hypertension(ISH)in the elderly,and effect of Losartan potassium .Method Serum uric acid level were assessed spectrophotometrically using enzymatic methods in 85 ISH patients and 51 health controls.Serum uric acid level and blood pressue were compared respectively before and after the treatment of losartan potassium and Benzepril.Result Uric acid level was higher in patients with ISH than that in control group (P< 0.01).No significant difference was found between Losartan potassium and Benzepril group on the effect of lowering blood pressure .After antihypertensive treatment,uric acid level in Losartan group was significantly lower than that in Benzepril group(P< 0.01).Conclusion Uric acid level was marked higher in ISH in the elderly;Losartan prtassium has an additional benefit of some uricosuric effects besides the antihypertensive effect. |
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| Keywords: | hvoertension uric acid losartanootassium |
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