| 龙胆苦甙对小鼠肝细胞脂质过氧化的影响 |
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| 引用本文： | 林原,刘玉华,苏成业,李绵平. 龙胆苦甙对小鼠肝细胞脂质过氧化的影响[J]. 大连医科大学学报, 1991, 0(3) |
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| 作者姓名： | 林原 刘玉华 苏成业 李绵平 |
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| 作者单位： | 大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室 |
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| 摘 要： | 龙胆苦甙对正常小鼠肝脏脂质过氧化无明显影响,但可显著降低饥饿小鼠肝脏脂质过氧化。饥饿小鼠肝细胞体外孵育结果表明,龙胆苦甙对小鼠肝细胞脂质过氧化的抑制作用与剂量呈正相关。龙胆苦甙对CCl_4所致肝脏脂质过氧化升高有明显的降低作用。
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| 关 键 词： | 龙胆苦甙 脂质过氧化 CCl_4 丙二醛 |
THE EFFECT OF GENTIOPICROSIDE ON LIPID PEROXIDATION OF MICE LIVER |
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| Lin Yuan. THE EFFECT OF GENTIOPICROSIDE ON LIPID PEROXIDATION OF MICE LIVER[J]. Journal of Dalian Medical University, 1991, 0(3) |
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| Authors: | Lin Yuan |
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| Affiliation: | Lin Yuan Department of pharmacology,Dalian Medical College |
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| Abstract: | Gentiopicroside (GP)has no obvious effect on lipid peroxidation (LPO) of mice liver under normal condition. GP significantly reduced liver LPO of fasted mice. The result of culture in vitro of mice hepatocytc indicated that GP significantly reduced LPO and the dosage and effect are linear. GP significantly lowered liver LPO of mice elevated by CCl_4. |
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| Keywords: | gentiopicroside lipid peroxydation(LPO) CCl_4 malondialdehyde |
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