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血清胱抑素C与糖尿病肾病
引用本文:韩颖,李素芬,刘艳. 血清胱抑素C与糖尿病肾病[J]. 国外医学:内分泌学分册, 2014, 0(3): 207-210
作者姓名:韩颖  李素芬  刘艳
作者单位:大港油田总医院内分泌科,天津300280
摘    要:血清胱抑素C是一种半胱氨酸蛋白酶抑制剂,由机体所有有核细胞以恒定的速率产生,其相对分子质量小,可被肾小球自由滤过,在近端肾小管被代谢.血清胱抑素C作为一种内源性标志物,可以较早的反映肾小球滤过率的变化,故其在糖尿病肾病早期诊断中有重要的价值.

关 键 词:胱抑素C  糖尿病肾病  肾小球滤过率

Relationship between serum cystatin C and diabetic nephropathy
Affiliation:Han Ying,Li Sufen,Liu Yah. (Department of Endocrinology,Dagang Oil Field General Hospital, Tianjin 300280, China)
Abstract:Cystatin C, a cysteine proteinase inhibitor, is produced at a constant rate by nucleated cells, and is freely filtered by the renal glomeruli, metabolized by the proximal tubule.As an endogenous serum markers, cystatin C can reflect the early changes of glomerular filtration rate, so it has important value in early diagnosis of diabetic nephropathy.
Keywords:Cystatin C  Diabetic nephropathy  Glomerular filtration rate
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