| 甲状腺功能亢进症伴严重药物性胆汁郁积性肝炎1例并文献复习 |
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| 引用本文： | 曹雯,郑仁东,陈国芳,包薇萍,刘超.甲状腺功能亢进症伴严重药物性胆汁郁积性肝炎1例并文献复习[J].国外医学：内分泌学分册,2014(3):214-216. |
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| 作者姓名： | 曹雯 郑仁东 陈国芳 包薇萍 刘超 |
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| 作者单位： | 中国中医科学院江苏分院、南京中医药大学附属中西医结合医院内分泌代谢病院区,南京210028 |
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| 摘 要： | 甲状腺功能亢进症（甲亢）本身可导致肝功能损害,而抗甲状腺药物亦可引起肝功能损伤.但出现严重药物性胆汁郁积性肝炎的病例比较少见,临床治疗较为困难.本院收治1例,在治疗甲亢的基础上,采用甲强龙静脉脉冲冲击联合口服强的松的方案,降低患者胆红素水平,使肝功能恢复正常,甲亢亦得以控制.
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| 关 键 词： | 甲状腺功能亢进症 药物性胆汁郁积性肝炎 糖皮质激素 |
One case of hyperthyroidism with severe drug-induced cholestasis hepatitis and literature review |
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| Cao Wen,Zheng Rendong,Chen Guofang,Bao Weiping,Liu Chao.One case of hyperthyroidism with severe drug-induced cholestasis hepatitis and literature review[J].Foreign Medical Sciences(Section of Endocrinology),2014(3):214-216. |
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| Authors: | Cao Wen Zheng Rendong Chen Guofang Bao Weiping Liu Chao |
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| Institution: | .( Endocrine and Diabetes Center,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Nanjing University of Traditional Chinese Medicine, Jiangsu Branch of China Academy of Chinese Medical Scienee,Nanjing 210028, China) |
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| Abstract: | Hyperthyroidism can cause liver damage,while anti-thyroid drugs can also cause liver dysfunction. Severe case of drug-induced cholestasis hepatitis is rare, difficult to treat. Here we report a case with drug-induced cholestasis hepatitis. On the basis of the treatment of hyperthyroidism, intravenous methyl- prednisolone pulse therapy combined with oral prednisone was used to reduce bilirubin levels in patients, the- refore the liver function of the patient returned back to normal, and the hyperthyroidism was controlled. |
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| Keywords: | Hyperthyroidism Drug-induced cholestasis hepatitis Glucocorticoids |
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