| 大鼠背根神经节内kv2.1 mRNA和kv4.2 mRNA的表达 |
| |
| 引用本文： | 王劼,刘才栋,沈馨亚,彭裕文. 大鼠背根神经节内kv2.1 mRNA和kv4.2 mRNA的表达[J]. 解剖学研究, 2004, 26(1): 35-38 |
| |
| 作者姓名： | 王劼 刘才栋 沈馨亚 彭裕文 |
| |
| 作者单位： | 复旦大学上海医学院解剖与组织胚胎学系,上海,200032;复旦大学上海医学院解剖与组织胚胎学系,上海,200032;复旦大学上海医学院解剖与组织胚胎学系,上海,200032;复旦大学上海医学院解剖与组织胚胎学系,上海,200032 |
| |
| 摘 要： | 目的 了解kv2 1和kv4 2型钾离子通道在背根神经节的表达。方法 应用原位杂交方法观察背根神经节内细胞膜钾离子kv2 1和kv4 2型通道的mRNA阳性神经结构的表达。结果 腰 3～ 5背根神经节内均有kv2 1和kv4 2mRNA阳性神经元的表达 ,kv4 2mRNA阳性神经元的数量和总面积明显多于kv2 1阳性神经元。结论 kv2 1和kv4 2型钾离子通道可能参与了背根神经节对外周传入信息的传递和调制。
|
| 关 键 词： | 钾离子通道 背根神经节 大鼠 |
| 修稿时间： | 2003-07-12 |
Expression of ky2.1 and ky4.2 mRNA in rat dorsal root ganglion |
| |
| Wang Jie,Liu Caidong,Shen Xinya,Peng Yuwen. Expression of ky2.1 and ky4.2 mRNA in rat dorsal root ganglion[J]. Anatomy Research, 2004, 26(1): 35-38 |
| |
| Authors: | Wang Jie Liu Caidong Shen Xinya Peng Yuwen |
| |
| Affiliation: | Wang Jie,Liu Caidong,Shen Xinya,Peng Yuwen. Department of Anatomy,Histology and Embryology,Shanghai Medical School of Fudan University,Shanghai 200032 China |
| |
| Abstract: | Objective In order to understand function of kv2.1 and kv4.2 type K + ion channel in DRG. Methods kv2.1 and kv4.2 type K + ion channel was showed with ISHH on the DRG in rat. Results The expression of kv2.1 mRNA-and kv4.2 mRNA-positive neurons structure in dorsal root ganglia were viewed in L3～5 DRG. The quantity and general area of kv4.2 mRNA-positive neurons in dorsal root ganglias were showed more to kv2.1 mRNA-positive neurons structure. Conclusions Opening of kv2.1 and kv4.2 type K+ ion channel probably partake in the transmission and modulation to peripheral afference in the dorsal root ganglia. |
| |
| Keywords: | K + ion channel Dorsal root ganglion Rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
