Microneedles with Intrinsic Immunoadjuvant Properties: Microfabrication,Protein Stability,and Modulated Release |
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| Authors: | Alexander K. Andrianov Alexander Marin Daniel P. DeCollibus |
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| Affiliation: | (1) Research & Development, Apogee Technology, Inc., 129 Morgan Drive, Norwood, Massachusetts 02062, USA |
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| Abstract: | Purpose Intradermal immunization using microneedles requires compatible immunoadjuvant system. To address this challenge, we investigated microneedles coated with polyphosphazene polyelectrolyte, which served both as microfabrication material and an immunoadjuvant compound. |
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