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体外循环中多核粒细胞肺隔离与肺损伤关系的临床研究
引用本文:杨宁,田子朴,袁宏声,石应康,梁少伟,周清华,罗传兴,黄旭中,肖锡俊,杨健,闵龙秋,吴淑红,王泉云,张慈忱.体外循环中多核粒细胞肺隔离与肺损伤关系的临床研究[J].华西医学,1992(4).
作者姓名:杨宁  田子朴  袁宏声  石应康  梁少伟  周清华  罗传兴  黄旭中  肖锡俊  杨健  闵龙秋  吴淑红  王泉云  张慈忱
作者单位:川北医学院,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院胸心外科,华西医大附一院麻醉科,华西医大附一院麻醉科,华西医大附一院麻醉科,华西医大附一院麻醉科
摘    要:本文测定30例体外循环(CPB)心脏直视手术病人循环粒细胞数,观察其中9例病人肺活检并与6例闭式心脏手术病人肺活检比较。结果表明:只有当肺循环重建时才出现明显的多核粒细胞(PMN′s)跨肺差,并伴有大量的PMN′s在肺毛细血管内聚集及肺组织超微结构的损伤性改变。

关 键 词:体外循环  多核粒细胞  肺隔离  肺损伤

The Clinical Study on the Relationship between Pulmonary Seqestration of Polymorphonuclear Leukocytes and Lung Injury during Cardiopulmonary Bypass
Yang Lin,Tain Zipu,Yuan Hongsheng,et al.The Clinical Study on the Relationship between Pulmonary Seqestration of Polymorphonuclear Leukocytes and Lung Injury during Cardiopulmonary Bypass[J].West China Medical Journal,1992(4).
Authors:Yang Lin  Tain Zipu  Yuan Hongsheng  
Institution:Yang Lin,Tain Zipu,Yuan Hongsheng,et al Department of Thoracic Cardiovascular Surgery,The lst University Hospital,West China University of Medical Sciences,Chengdu
Abstract:In this study, determination of the leukocyte counts in the circulation during cardiopulmonary bypass (CPB) has been Carried out in 30 cases with heart disease and lung biopsies were done examined in 9 after CPB and 6 cases with closed cardiac surgery as control. The results showed that a significant transpulmonary difference of polymorphonuclear leukocytes(PMN's) existed only when the pulmonary circulation has been recovered, concomitant with both significant PMN's aggregation in the pulmonary microvasculature and ultrastructural injuries of the lung tissure.These results suggested that the pulmonary PMN's sequestration might play an important role in the acute lung injuries secondary to CPB.
Keywords:Lung injury  Cardiopulmonary bypass  Polymorphonuclear leukocytes
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