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2型糖尿病患者超敏C反应蛋白和尿微量蛋白检测的临床意义
引用本文:陈红霞,楼晓佳,周莉莉.2型糖尿病患者超敏C反应蛋白和尿微量蛋白检测的临床意义[J].浙江医学,2010,32(2):183-184,300.
作者姓名:陈红霞  楼晓佳  周莉莉
作者单位:温州医学院附属东阳医院内分泌科,322100
摘    要:目的 探讨血清超敏C-反应蛋白(hs-CRP)和尿微量白蛋白(mAlb)在2型糖尿病早期肾病诊断中的应用价值.方法 测定41例2型糖尿病患者和32例健康体检者(正常对照组)外周血hs-CRP和mAlb的水平,并比较两者间的相关性.结果 2型糖尿病组血清hs-CRP和mAlb水平均明显高于正常对照组(P〈0.01);hs-CRP和mAlb存在明显正相关性(r=0.769,P〈0.01).结论 检测血清hs-CRP和mAlb水平对早期诊断糖尿病肾病具有临床价值.

关 键 词:超敏C-反应蛋白  微量白蛋白  2型糖尿病  糖尿病肾病

Diagnostic significance of high-sensitive c-reactive protein and urinary microalbumin in patients with type 2 diabetes
CHEN Hongxia,LOU Xiaojia,ZHOU Lili.Diagnostic significance of high-sensitive c-reactive protein and urinary microalbumin in patients with type 2 diabetes[J].Zhejiang Medical Journal,2010,32(2):183-184,300.
Authors:CHEN Hongxia  LOU Xiaojia  ZHOU Lili
Institution:(Department of Endocrinology, Affiliated Dongyang Hospital, Wenzhou Medical College, Jinhua 322100, China)
Abstract:Objective To evaluate the clinical significance of the serum high-sensitive c-reactive protein (hCRP) and urinary microalbumin (mAIb) in type 2 diabetes. Methods The serum levels of hCRP and Urinary mAIb were determined in 41 patients of type 2 diabetes and 32 healthy volunteers. Results The serum hCRP levels and urinary mAIb were significantly higher than those of control group ( P〈O.01 ) ;Serum hCRP levels were positively correlated with urinary mAlb ( P〈0.01 ). Conclusion The detection of serum high-sensitive C-reactive protein and urinary microalbumin may have diagnostic value for early kidney damage in type 2 diabetes.
Keywords:High-sensitive C-reactive protein Microalbumin Type 2 diabetes Diabetic nephropathy
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