锯叶棕果实提取物治疗BPH引起的下尿路症状疗效观察

目的:探讨锯叶棕果实提取物治疗BPH引起的下尿路症状的疗效。方法:采用锯叶棕果实提取物单药治疗30例前列腺增生伴下尿路症状患者8周,分别比较患者治疗前后的最大尿流率、前列腺体积、剩余尿量、IPSS评分及QOL评分的变化情况。结果:治疗8周后,患者的最大尿流率、剩余尿量、IPSS评分及QOL评分均有明显改善,前列腺体积则无明显变化。所有患者均无明显不良反应。结论:锯叶棕果实提取物能有效改善BPH患者的下尿路症状。

Clinical efficacy of saw palmetto extract in the treatment of benign prostatic hyperplasia patients with lower urinary tract symptoms

Objective:To evaluate the clinical efficacy of saw palmetto extract in the treatment of benign prostatic hyperplasia(BPH) patients with lower urinary tract symptoms(LUTS).Methods:30 BPH patients with LUTS were treated with saw palmetto extract 160mg twice a day for 8 weeks.We compared the maximum urinary flow rates(Qmax),Volume of the prostate(V),International Prostate Symptom Scores(IPSS),Quality of Life indexes(QOL) and post-void residual urine(PVR) before and after the treatment.Results:After 8 weeks medication,the Qmax,IPSS,QOL and PVR of the patients have significantly difference compared to which before the treatment.No patients experienced the adverse event.Conclusions:Saw palmetto extract is effective and safe in the treatment of BPH patients with LUTS.