Sustained ventricular tachycardia: Evidence for protected localized reentry |
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Authors: | Mark E. Josephson Leonard N. Horowitz Ardeshir Farshidi Scott R. Spielman Eric L. Michelson Allan M. Greenspan |
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Affiliation: | From the Electrophysiology Laboratory, Hospital of the University of Pennsylvania, Cardiovascular Section, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania USA |
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Abstract: | The components of the reentrant circuit were evaluated in 26 patients In whom sustained ventricular tachycardia could be reproducibly Initiated or terminated, or both. Observations suggesting that the proximal His Purkinje system was not a requisite component included (1) lack of requirement for retrograde His-Purkinje delay or bundle branch reentry, or both, for initiation of the tachycardia; (2) anterograde depolarization of the His bundle during ventricular tachycardia without alteration of the QRS configuration or cycle length; and (3) the presence of random retrograde His potentials during the tachycardia. Evidence that the reentrant circuit was localized to a small area of the ventricles included (1) the ability to capture large segments of the ventricles transiently or continuously with ventricular stimulation without affecting the tachycardia, and (2) the occurrence of intermittent or continuous supraventricular capture either spontaneously or with atrlal pacing without effect on the tachycardia. These findings suggest that the reentrant circuit must be small, electro-cardiographically silent and relatively protected. |
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Keywords: | Address for reprints: Mark E. Josephson MD 666 White Building Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia Pennsylvania 19104. |
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