| 低剂量电离辐射对松果腺细胞凋亡的影响 |
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| 引用本文： | 马琳,李啸峰,张铭. 低剂量电离辐射对松果腺细胞凋亡的影响[J]. 华夏医学, 2007, 20(1): 1-2 |
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| 作者姓名： | 马琳 李啸峰 张铭 |
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| 作者单位： | 中山大学附属第五医院,广东,珠海,519000;吉林大学公共卫生学院,吉林,长春,130021 |
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| 摘 要： | 目的：通过低剂量辐射兴奋效应的动物模型，进一步探讨低剂量X射线全身照射对小鼠松果腺细胞凋亡的影响。方法：采用0．075Gy X射线全身照射后不同时间间隔取松果腺，采用流式细胞术（FCM）检测照射后不同时间松果腺细胞凋亡百分率的时程变化。结果：低剂量电离辐射全身照射12h、24h、48h后松果腺细胞凋亡百分率降低（P〈0．01）。结论：低剂量辐射可抑制松果腺细胞的凋亡。
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| 关 键 词： | 低剂量电离辐射 松果腺 细胞凋亡 |
| 文章编号： | 1008-2409(2007)01-0001-02 |
| 修稿时间： | 2006-11-03 |
Effect of low dose radiation on cell apoptosis of pineal gland |
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| MA Lin,LI Xiao-feng,ZHANG Ming. Effect of low dose radiation on cell apoptosis of pineal gland[J]. Acta Medicinae Sinica, 2007, 20(1): 1-2 |
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| Authors: | MA Lin LI Xiao-feng ZHANG Ming |
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| Affiliation: | MA Lin,LI Xiaofeng,ZHANG Ming The 5th Affiliated Hospital of Sun Yat-sen University,Zhuhai 519000,China |
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| Abstract: | Objective: To observe the effect of low dose radiation on cell apoptosis of pineal gland in mice.Methods: The percentage of the cell apoptosis was analyzed by flow cytometry after staining of pineal gland with propidium iodine(PI) after whole body irradiation with 0.075Gy X-rays.Results: After whole body irradiation of low dose radiation,the percentage of the cell apoptosis of pineal gland decreased in 12h,24h,48h(P<0.01).Conclusion: Low dose radiation can inhibit the apoptosis of pineal gland cells. |
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| Keywords: | low dose radiation pineal gland cell apoptosis |
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