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miR‐130b directly targets ARHGAP1 to drive activation of a metastatic CDC42‐PAK1‐AP1 positive feedback loop in Ewing sarcoma |
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| Authors: | Laura Satterfield Ryan Shuck Lyazat Kurenbekova Wendy Allen‐Rhoades Dean Edwards Shixia Huang Kimal Rajapakshe Cristian Coarfa Lawrence A. Donehower Jason T. Yustein |
| Affiliation: | 1. Texas Children's Cancer and Hematology Centers and The Faris D. Virani Ewing Sarcoma Center, Baylor College of Medicine, Houston, TX;2. Integrative Molecular and Biological Sciences Program, Baylor College of Medicine, Houston, TX;3. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX;4. Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX;5. Department of Molecular Virology & Microbiology, Baylor College of Medicine, Houston, TX |
| Abstract: | |
| Keywords: | metastasis microRNA PAK1 Ewing sarcoma CDC42 |