| Analysis of Plasma Fibrinolysis in the Patients with Acute Cerebral Infarction |
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| 引用本文： | 张颖冬,刘锡民,蔡转,杨明山.Analysis of Plasma Fibrinolysis in the Patients with Acute Cerebral Infarction[J].华中科技大学学报(医学英德文版),1995,15(2):68-72. |
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| 作者姓名： | 张颖冬 刘锡民 蔡转 杨明山 |
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| 作者单位： | Department of Neurology，Tongji Hospital，Tongji Medical University，Wuhan 430030 |
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| 摘 要： | ＡｎａｌｙｓｉｓｏｆＰｌａｓｍａＦｉｂｒｉｎｏｌｙｓｉｓｉｎｔｈｅＰａｔｉｅｎｔｓｗｉｔｈＡｃｕｔｅＣｅｒｅｂｒａｌＩｎｆａｒｃｔｉｏｎＺＨＡＮＧＹｉｎｇ－ｄｏｎｇ（张颖冬）；ＬＩＵＸｉ－ｍｉｎ（刘锡民）；ＣＡＩＺｈｕａｎ（蔡转）；ＹＡＮＧＭｉｎｇ－...
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| 收稿时间： | 24 November 1994 |
Analysis of plasma fibrinolysis in the patients with acute cerebral infarction |
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| Shang Ying-dong,Liu Xi-min,Cai Zhuan,Yang Ming-shan.Analysis of plasma fibrinolysis in the patients with acute cerebral infarction[J].Journal of Zuazhong University of Science and Technology: Medical Edition,1995,15(2):68-72. |
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| Authors: | Shang Ying-dong Liu Xi-min Cai Zhuan Yang Ming-shan |
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| Institution: | (1) Deparlment of Neurology, Tongji Hospital, Tongji Medical University, 430030 Wuhan;(2) Present address: Department of Neurology, the First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, 510080 Guangzhou |
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| Abstract: | In the present study, the plasma fibrinolytic activity in 30 cases of cortical artery territory cerebral infarction (CACI) and 32 cases of perforating artery territory cerebral infarction (PACI) within 3 days after ictus, and 30 sexand age-matched controls without cardio-cerebrovascular diseases were evaluated by a comprehensive panel of assay, including the plasma tPA activity, PAI activity, endothelial capacity of tPA release and PAI/tPA ratio. The results showed that the plasma fibrinolysis and the endothelial potential to release tPA responding to stimulation in boch subtypes of the patients were significantly lower than those in the controls, which provide. the theoretical basis for carrying out the thrombolytic therapy in the ischemic stroke. And the study also suggested that increased Plasma PAI activity could increase the risk of AS chrombotic events with increased serum triglyceride level. |
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| Keywords: | cerebral infarction tissue-plasminogen activator (tPA) plasminogen activator inhibitor (PAI) |
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