高分辨核磁共振成像在预测儿童局灶性皮质发育不良手术效果中的价值

目的 探讨高分辨核磁共振成像(MRI)在儿童局灶性皮质发育不良(Focal cortical dysplasia,FCD)手术中的效果及价值.方法 回顾性分析2013年7月-2018年7月于山东大学齐鲁儿童医院经手术病理证实的143例FCD患儿的MRI及临床资料,年龄5月龄～12.5岁,既往无治疗史,分析其MRI征象:...

The value of high-resolution MRI in predicting the outcome of surgery for focal cortical dysplasia in children

Objective To explore the value of high-resolution Magnetic resonance imaging(MRI)imaging in predicting the surgical effect of Focal cortical dysplasia(FCD)in children.Methods The MRI and clinical data of 143 children with FCD confirmed by surgery and pathology in Qilu Children’s Hospital of Shandong University from July2013 to July 2018 were analyzed retrospectively,and the MRI signs were analyzed,and the patients were grouped according to different signs to analyze the satisfaction of postoperative epilepsy control in each group.Results Among the 9 groups of children,MRI signs in the group with better postoperative epilepsy control were those with obvious focal gray matter blurring and cortical thickening and combined with Transmantle sign.The MRI signs in the group with poor postoperative results were mild focal gray matter blurring and cortical structure thinning,and those with abnormal sulcus and gyrus morphology,the postoperative effect of patients with only abnormal sulci and gyrus as the main MRI manifestations was significantly better than those with other signs,and the above differences were statistically significant(P<0.05).Conclusion The high-resolution MRI of children with FCD had a certain specificity,and it is feasible to predict the satisfaction of postoperative epilepsy control from the perspective of MRI signs,which is an important indicator of surgical prognosis.