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| 慈竹提取物对心肌缺血大鼠的影响 | |
| 引用本文： | 郭英,谢建平,云宇,马加庆,沈志强,莫尚武,莫正纪. 慈竹提取物对心肌缺血大鼠的影响[J]. 时珍国医国药, 2011, 22(8): 1824-1825. DOI: 10.3969/j.issn.1008-0805.2011.08.010 |
| 作者姓名： | 郭英 谢建平 云宇 马加庆 沈志强 莫尚武 莫正纪 |
| 作者单位： | 1. 昆明医学院·基础医学院,云南昆明650500;四川大学·华西药学院,四川成都610041 2. 云南省药物研究所,云南昆明,650111 3. 昆明医学院·基础医学院,云南昆明650500 4. 昆明医学院·云南省天然药物药理重点实验室,云南昆明650500 5. 四川大学原子核科学技术研究所,四川成都,610041 6. 四川大学·华西药学院,四川成都610041 |
| 摘 要： | 目的研究慈竹提取物对大鼠急性心肌缺血的影响。方法采用异丙肾上腺素致心肌缺血的方法,研究慈竹提取物对大鼠急性心肌缺血的影响。结果 慈竹提取物口服给药能抑制异丙肾上腺素致心肌缺血大鼠J点的偏移、心率的变化及左室舒张末期压的变化。结论 慈竹提取物对心肌缺血大鼠的心脏有保护作用。 |
| 关 键 词： | 慈竹提取物 异丙肾上腺素 心肌缺血 |
Effects of Sinocalamus affinis Extract on Acute Myocardial Ischemia in Rats |
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| GUO Ying,XIE Jian-ping,YUN Yu,MA Jia-qing,SHEN zhi-qiang,MO Shang-wu,MO Zheng-ji. Effects of Sinocalamus affinis Extract on Acute Myocardial Ischemia in Rats[J]. Lishizhen Medicine and Materia Medica Research, 2011, 22(8): 1824-1825. DOI: 10.3969/j.issn.1008-0805.2011.08.010 | |
| Authors: | GUO Ying XIE Jian-ping YUN Yu MA Jia-qing SHEN zhi-qiang MO Shang-wu MO Zheng-ji |
| Affiliation: | GUO Ying1,2,XIE Jian-ping3,YUN Yu1,MA Jia-qing1,SHEN Zhi-qiang4,MO Shang-wu5,MO Zheng-ji2*(1.Dept.of Pharmacology,Basic Medical College,Kunming Medical University,Kunming 650500,China,2.Dept.of Pharmacology,West China School of Pharmacolog,Sichuan Universit,Chengdu 610041,3.Yunnan Institute of Materia Medica,Kunming 650111,4.Yunnan Key Laboratory of Pharmacology for Natural Products,5.Scientific and Technical Institute of Atomic Nucleus,Sichuan Uni... |
| Abstract: | Objective To investigete the effects of Sinocalamus affinis extract on myocardial ischemia in rats.Methods Acute myocardial ischemia was caused by isoprenaline in rats.Results Sinocalamus affinis extract peros could inhibit drift of point J,change heart rate and left ventricular end-diastolic pressure in myocardial ischemia rats.Conclusion Sinocalamus affinis extract has protective effect on myocardial ischemia. |
| Keywords: | Sinocalamus affinis extract Isoprenaline Myocardial ischemia |
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