| 胡萝卜多糖抗炎及体外抗氧化作用研究 |
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| 引用本文： | 刘立新,张羽男,沙靖全,柴佳丽. 胡萝卜多糖抗炎及体外抗氧化作用研究[J]. 时珍国医国药, 2011, 22(10). DOI: 10.3969/j.issn.1008-0805.2011.10.008 |
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| 作者姓名： | 刘立新 张羽男 沙靖全 柴佳丽 |
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| 作者单位： | 佳木斯大学药学院,黑龙江佳木斯,154007 |
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| 基金项目： | 国家自然科学基金(No.20901031) |
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| 摘 要： | 目的 研究胡萝卜多糖的抗炎和抗氧化作用,为利用胡萝卜工业化生产多糖药用成分提供科学依据.方法 抗氧化试验采用Fenton反应法和烘箱储藏法,通过比较吸光度和POV值研究其抗氧化活性；抗炎实验采用二甲苯致耳肿胀法,通过比较小鼠耳肿胀度和抑制率考察其抗炎活性.结果 胡萝卜多糖具有较强的清除·OH和抗自氧化作用以及能显著性抑制二甲苯的致炎作用,而且具有明显的量效关系.结论 胡萝卜多糖具有显著的抗氧化、抗炎活性.
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| 关 键 词： | 胡萝卜多糖 抗炎 抗氧化 |
Anti - inflammatory Effects and in vitro Antioxidant Activity of Polysaccharides from Carrot |
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| LIU Li-xin,ZHANG Yunan,SHA Jing-quan,CHAI Jia-li. Anti - inflammatory Effects and in vitro Antioxidant Activity of Polysaccharides from Carrot[J]. Lishizhen Medicine and Materia Medica Research, 2011, 22(10). DOI: 10.3969/j.issn.1008-0805.2011.10.008 |
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| Authors: | LIU Li-xin ZHANG Yunan SHA Jing-quan CHAI Jia-li |
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| Affiliation: | LIU Li-xin,ZHANG Yunan,SHA Jing-quan*,CHAI Jia-li(School of Pharmacological Sciences,Jiamusi University,Jiamusi 154007,China) |
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| Abstract: | ObjectiveTo study the anti-inflammatory effects and in vitro antioxidant activity of polysaccharide from carrot in this paper,and to provide the scientific basis for production of medicinal ingredients of polysaccharides from carrot. MethodsFenton reaction and oven storage were employed in the antioxidant ability test.The antioxidant activity of polysaccharides in carrot was studied by comparing the absorbance and POV values.The anti-inflammatory experiment was adopted by xylene-induced ear edema.The anti-i... |
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| Keywords: | Polysaccharides in carrot Anti-inflammatory Antioxidant activity |
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