| 微波辅助葛根素衍生物酸水解研究 |
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| 引用本文： | 汪洋,周芳,张越非,李倩,池汝安.微波辅助葛根素衍生物酸水解研究[J].时珍国医国药,2011,22(8). |
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| 作者姓名： | 汪洋 周芳 张越非 李倩 池汝安 |
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| 作者单位： | 1. 武汉工程大学化工与制药学院·绿色化工过程省部共建教育部重点实验室·湖北省新型反应器与绿色化学工艺重点实验室,湖北武汉430073
2. 武汉工程大学国际学院,湖北武汉,430073 |
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| 基金项目： | 国家自然科学基金青年基金项目，湖北省自然科学基金重点项目，湖北省教育厅优秀中青年人才项目，湖北省高等教学优秀中青年科技创新团队项目，武汉工程大学青年科学基金项目 |
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| 摘 要： | 目的 采用微波辅助盐酸水解葛根素衍生物,并优化其工艺.方法 采用单因素实验和正交实验,以葛根素的含量为评价指标,考察反应时间、反应温度、盐酸浓度、微波功率对水解的影响.结果 优化后的较佳工艺条件为:反应时间10min,反应温度80℃,盐酸浓度4％,微波功率800 W.结论 微波辅助盐酸水解葛根素衍生物是一种高效节能的方法.在优化条件下,葛根素的含量达到15.99％.
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| 关 键 词： | 葛根素衍生物 葛根素 酸水解 微波加热 |
Process of Hydrolyzing Derivatives of puerarin in Acid by Microwave - assisted Method |
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| WANG Yang,ZHOU Fang,ZHANG Yue-fei,LI Qian,CHI Ru-an.Process of Hydrolyzing Derivatives of puerarin in Acid by Microwave - assisted Method[J].Lishizhen Medicine and Materia Medica Research,2011,22(8). |
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| Authors: | WANG Yang ZHOU Fang ZHANG Yue-fei LI Qian CHI Ru-an |
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| Institution: | WANG Yang1,ZHOU Fang2,ZHANG Yue-fei1,LI Qian1,CHI Ru-an1*(1.School of Chemical Engineering & Pharmaceutics,Wuhan Institute of Technology,Key Laboratory for Green Chemical Process of Ministry of Education,Hubei Key Lab of Novel Reactor & Green Chemical Technology Wuhan 430073,China,2.School of International Education,Wuhan,430073,China) |
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| Abstract: | Objective To hydrolyze derivatives of puerarin in acid by microwave-assisted heating method and optimize the process.Methods The reacting time,reacting temperature,hydrochloric acid concentration,and microwave power were optimized through the single factor experiments and orthogonal experiments with the content of puerarin as the evaluation index.Results The optimal technological parameters of hydrolyzing total flavone were that: the reaction time,the reaction temperature,the hydrochloric acid concentration... |
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| Keywords: | Derivatives of puerarin Puerarin Acid hydrolysis Microwave-assisted heating method |
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