|
|||||
|
|
| 元宝草化学成分的分离与鉴定 | |
| 引用本文： | 康佳敏,欧阳胜,肖炳坤,杨建云,黄荣清.元宝草化学成分的分离与鉴定[J].时珍国医国药,2011,22(11):2641-2642. |
| 作者姓名： | 康佳敏 欧阳胜 肖炳坤 杨建云 黄荣清 |
| 作者单位： | 1. 军事医学科学院放射与辐射医学研究所,北京100850;江西中医学院中药化学教研室,江西南昌330004 2. 江西中医学院中药化学教研室,江西南昌,330004 3. 军事医学科学院放射与辐射医学研究所,北京,100850 |
| 基金项目： | 国家科技重大专项"重大新药创新"综合性新药研究开发技术大平台，国家自然科学基金 |
| 摘 要： | 目的对元宝草进行化学成分研究。方法采用硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等方法进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果分离得到9个化合物,分别鉴定为1,7-二羟基酮①、1,3,5,6-四羟基酮②、5,7,4’-三羟基-黄酮醇③、5,7,3’,4’-四羟基-黄酮醇④、金丝桃苷⑤、山萘酚-3-0-葡萄糖苷⑥、对羟基苯甲酸⑦、3,4-二羟基苯甲酸⑧、白桦脂酸⑨。结论化合物7,9为首次从该植物中分离得到。 |
| 关 键 词： | 元宝草 化学成分 分离 鉴定 |
Isolation and Identification of the Chemical Constituents from the Hypericum sampsonii Hance |
|
| KANG Jia-min,OUYANG Sheng,XIAO Bing-kun,YANG Jian-yun,HUANG Rong-qing.Isolation and Identification of the Chemical Constituents from the Hypericum sampsonii Hance[J].Lishizhen Medicine and Materia Medica Research,2011,22(11):2641-2642. | |
| Authors: | KANG Jia-min OUYANG Sheng XIAO Bing-kun YANG Jian-yun HUANG Rong-qing |
| Institution: | KANG Jia-min 1.2,OUYANG Sheng2,XIAO Bing-kun1,YANG Jian-yun1,HUANG Rong-qing1 (1.Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing,100850,China,2.Jiangxi University of Traditional Chinese Medicine,Nanchang,330004,China) |
| Abstract: | Objective To study the chemical constituents of Hypericum sampsonii Hance. Methods The compounds were isolated by silica gel column chromatography,gel column chromatography and recrystallization, and their structures were elucidated by means of spectral analyses. Results Nine compounds were identified as 1,7-dihydroxyxanthone(1),1,3,5,6-tetrahydroxyxanthone(2),5,7,4′-trihydroxyflavonol(3),5,7,3′,4′-tetrahydroxyflavonol(4),hyperin(5),kaempferol-3-O-glucosylside(6),p-hydroxybenzoic acid(7),3,4-dihydroxybenzoic acid(8),betulinic acid(9). Conclusion Compound 7and 9 are isolated from the plants of Hypericum sampsonii Hance for the first time. |
| Keywords: | Hypericum sampsonii Hance Chemical composition Isolation Identification |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |