Ⅰ、Ⅱ类切口围手术期抗菌药物合理用药干预性研究

目的 为探讨围手术期抗菌药物应用方案实施的可行性。方法 设干预组、非干预组进行对照研究。结果 干预后其平均药费、平均抗菌药费均降低，尤其平均抗菌药费明显降低，妇科组更为突出。干预后使用抗菌药物的合理率有显著好转（P＜0．01）。使用抗菌药物不合理原因干预前差异显著性。干预前后医院感染发生率无差异。结论 本研究所实物 合理用药措施具有可行性和有效性，对促进安全、有效、经济、合理地使用抗菌药物起到了积极的作用，为医院降低单病种费用提供了一效且可行的模式。

Rational Utilization of Antibiotics for the Perioperative Patients of Ⅰand Ⅱ Types Incisions: An Interventional study

Objective To study the feasibility on rational drug use of antibiotics at perioperative period. METHODS To compare the results of the intervened group with that of the non intervened one. RESULTS The average expense of all drugs and antibiotics in the intervened group are both lower than those in the non intervened one. Particularly, the average expense of antibiotics and the expense in the Department of Gynecology decrease much more obviously. The ratio of the rational utilization of antibiotics in the intervened group increases notably. The reasons of the irrationally utilizing antibiotics between the intervened group and the non intervened one are significantay different. The ratios of nosocomial infection between the two groups are without difference. CONCLUSIONS This intervention for rational antibiotics utilization is feasible and effective, which will promote the utilization of antibiotics more effective, more economic, and safer. Moreover, this intervention provides an effective and feasible pattern for reducing the expense in the single disease, so it will be beneficial to the patients, hospitals and the country.