| 不同退变程度腰椎间盘组织中一氧化氮和超氧化物歧化酶含量的变化及其意义 |
| |
| 引用本文： | 黄涛 付勤 张铁峰 王岩峰 顾海伦 沈涛. 不同退变程度腰椎间盘组织中一氧化氮和超氧化物歧化酶含量的变化及其意义[J]. 中国医科大学学报, 2005, 34(5): 473-474 |
| |
| 作者姓名： | 黄涛 付勤 张铁峰 王岩峰 顾海伦 沈涛 |
| |
| 作者单位： | [1]中国医科大学附属第一医院骨科,沈阳110001 [2]附属第二医院骨科,沈阳110001 |
| |
| 摘 要： | 目的:研究一氧化氮(NO)和超氧化物歧化酶(SOD)在不同退变程度腰椎间盘组织中含量的变化及其意义.方法:用分光光度法测定46例腰椎间盘突出症患者的腰椎间盘组织中的NO和SOD的含量并进行比较.结果:随腰椎间盘退变程度的加重腰椎间盘组织中NO含量升高,SOD含量减低.结论:腰椎间盘退变时,腰椎间盘组织中NO升高SOD降低,氧自由基损伤在腰椎间盘退变中发挥重要作用.
|
| 关 键 词： | 腰椎间盘 一氧化氮 超氧化物歧化酶 |
| 文章编号： | 0258-4646(2005)05-0473-02 |
| 收稿时间： | 2004-06-28 |
| 修稿时间： | 2004-06-28 |
Change and the clinical implication of nitric oxide and superoxide dismutase in degenerative lumbar intervertebral disc tissue |
| |
| HUANG Tao, FU Qin , ZHANG Tie-fng , WANG Yan-feng , GU Hai-lun , SHEN Tao. Change and the clinical implication of nitric oxide and superoxide dismutase in degenerative lumbar intervertebral disc tissue[J]. Journal of China Medical University, 2005, 34(5): 473-474 |
| |
| Authors: | HUANG Tao FU Qin ZHANG Tie-fng WANG Yan-feng GU Hai-lun SHEN Tao |
| |
| Affiliation: | 1. Department of Orthopedics, The First Affiliated Hospital, China Medical University, Shenyang 110001, China; 2. Department of Orthopedics, The Second Affiliated Hospital |
| |
| Abstract: | Objective: To investigate changes of nitric oxide(NO) and superoxide dismutase(SOD) in the degenerative lumbar intervertebral discs and to test the hypothesis that damage of oxide free radical involves in the degeneration of intervertebral disc.Methods: Forty-six degenerative lumbar discs were obtained from patients who had undergone the operation.All specimens were examined for NO and SOD with spectrophotography.Results: The contents of NO and SOD in the degenerative lumbar discs increased and decreased respectively with the aggravation of the degenerated degree of lumbar intervertebral discs.Conclusion: The expressions of more NO and less SOD take place along with the degeneration of the lumbar intervertebral disc.Damage of oxide free radicals plays a very important role in the degeneration of normal lumbar intervertebral disc tissues. |
| |
| Keywords: | lumbar intervertebral disc nitric oxide superoxide dismutase |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
