痛泻要方合四逆散加味治疗腹泻型肠易激综合征临床研究

目的：探讨痛泻要方合四逆散加味治疗腹泻型肠易激综合征的临床疗效。方法：将115例腹泻型肠易激综合征患者随机分为治疗组59例和对照组56例,治疗组口服痛泻要方合四逆散加味（方药组成：柴胡12 g,枳实10 g,防风10 g,陈皮10 g,生白术15 g,乌梅30 g,延胡索15 g,炒白芍15 g,炙甘草5 g）治疗;对照组口服匹维溴铵治疗。两组均以4周为1个疗程,治疗后观察临床疗效。结果：两组综合疗效比较治疗组有效率为93.2%,对照组有效率为57.1%,治疗组明显优于对照组（P〈0.05）;证候疗效比较治疗组有效率为98.3%,对照组有效率为67.9%,治疗组明显优于对照组（P〈0.05）。结论：痛泻要方合四逆散加味治疗腹泻型肠易激综合征疗效显著。

Clinical Study on the Treatment of D-IBS by Tongxieyaofang Decoction Combined with Modified Sini Powder

Objective：To explore the clinical effect of Tongxieyaofang decoction combined with modified Sini powder in the treatment of D-IBS.Methods：115 patients were randomly divided into two groups.The treatment group（59 cases） was given Tongxieyaofang decoction combined with modified Sini powder.（Composion：Radix bupleuri 12 g,Immature bitter orange 10 g,Divaricate Saposhnikovia root 10 g,Dried tangerine or orange peel 10 g,Raw rhizoma atractylodis macrocephalae 15 g,Dark Plum fruit 30 g,Rhizoma corydalis 15 g,Roasted rhizoma atractylodis macrocephalae 15 g,Radix glycyrrhizae 5 g）,while the control group（56 cases） was giver oral administration of Pinaverium Bromide.4 weeks as a course of treatment in the two groups.Results：The effective rate was 93.2% in the treatment group,while 57.1% in the control group for comprehensive effect.The treatment group was superior to the control group（P0.05）.The effective rate is 98.3% in the treatment group,while the control group 67.9% in syndrome effect（P0.05）.Conclusion：Tongxieyaofang decoction combined with modified Sini powder has a significant curative effect on D-IBS