HIV/AIDS合并HCV患者血红蛋白、肝功能与CD4+T细胞计数关系探讨

目的:探讨人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)合并丙型肝炎病毒(HCV)患者血红蛋白与肝功能、CD4+T细胞计数之间的相关性,以期运用观察血红蛋白判断HIV/AIDS合并HCV的预后.方法:采用回顾性分析方法将抗病毒治疗前的HIV/AIDS及HIV/AIDS合并HCV患者分别分为A、B、C组,进行肝功能、血红蛋白、CD4+T细胞计数的观察,予组间比较及统计学分析.结果:HIV/AIDS及HIV/AIDS合并HCV患者A、B、C组各组间贫血发生率有统计学差异(P＜0.05),HIV/AIDS组中随CD4+T细胞计数下降贫血发生率增高,HIV/AIDS合并HCV组中随CD4+T细胞计数下降贫血发生率有不同程度升高.HIV/AIDS及HIV/AIDS合并HCV各组间肝功能与CD4+T细胞计数无统计学差异(P＞0.05).结论:HIV/AIDS合并HCV发生贫血亦较为常见.

Relationship between Hemoglobin,Liver Function and Count of CD4~+ T Cell in Patients with HIV/AIDS Combined with HCV

Objective:To study the correlation of HIV/AIDS combined with HCV patients’ hemoglobin,liver function and CD4+T cell count,in result of which the hemoglobin quantity could be used to judge the prognosis of the patients who were HIV/AIDS combined with HCV.Methods:A certain number of patients who were infected HIV/AIDS and HIV/AIDS combined HCV were respectively divided into A,B and C groups.Before they were under the treatment of HAART,observing their liver function,hemoglobin and CD4+T cell count,making comparisons among groups and also to make statistical analysis.Results:There were statistically significant differences(P<0.05) in anemia rate in all groups of HIV/AIDS patients,and HIV/AIDS combined with HCV patients were divided into A,B and C.The anemia rate in groups of HIV/AIDS increased along with the decreasing of the CD4+T cell count,and in groups of HIV/AIDS combined with HCV,it increased varying degrees along with the decreasing CD4+T cell count.There was no statistically significant difference(P>0.05)in liver function and CD4+T cell count among each group of HIV/AIDS and HIV/AIDS combined with HCV.Conclusions:It was also commonly that HIV/AIDS combined with HCV patients prone to suffer from anemia,and with the decreasing of the CD4+T cell count,the anemia rate increased.