抗艾滋病毒生物活性天然多糖类化合物研究进展

目的：探讨抗艾滋病毒（HIV）生物活性天然多糖类化合物研究进展,为临床治疗艾滋病（AIDS）提供依据。方法：通过总结、归纳和分析近年来治疗艾滋病毒感染者和艾滋病患者（HIV/AIDS）的相关文献,对具有抗HIV生物活性的天然多糖类化合物的来源与种类、抗HIV机制、结构及其构效关系进行概括和总结,并探讨研究中存在的主要问题。结果：天然多糖类化合物广泛存在于自然界各类有机体中,具有多种重要的生物活性和药理作用,特别是其抗HIV活性,越来越受到科学界的重视。结论：对抗HIV活性天然多糖类化合物的研究为临床应用提供了理论基础。

Research Progress of Natural Polysaccharide Compounds with Anti-HIV Bioactivity

Objective：To investigate the research progress on natural polysaccharide compounds with anti-HIV bioactivity and provide the basis for the clinical treatment of AIDS.Methods：Through the summarization,induction and analysis of the literature on the treatment of HIV-infected people and AIDS patients in recent years,the sources and types of natural polysaccharide compounds with anti-HIV bioactivity,anti-HIV mechanism,structures,and its structure-activity relationships were summarized and the main problems in the study were discussed.Results：The compounds of the natural polysaccharides widely existed in various kinds of organisms of nature,with a variety of important biological activity and pharmacological effects,especially their anti-HIV activity,which was paid more and more attention by the scientific community.Conclusion：The study on natural polysaccharide compounds with anti-HIV bioactivity provides a theoretical basis for its clinical application.