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胰腺癌患者体内维生素E水平的改变
引用本文:王德丰,瞿晓慈,戴正庆. 胰腺癌患者体内维生素E水平的改变[J]. 南方医科大学学报, 2002, 22(3): 210-211
作者姓名:王德丰  瞿晓慈  戴正庆
作者单位:南通医学院附属医院,江苏南通,226001
摘    要:目的探讨维生素E(VitE)在胰腺癌患者体内改变及其作用机制。方法对不同胰腺病患者血清中VitE的浓度进行了比较分析。结果在胰腺病患者中,急性胰腺炎、慢性胰腺炎、胰腺癌患者血清中VitE的含量均显著低于正常对照组(P<0.05),胰腺癌组血清VitE显著低于急性胰腺炎、慢性胰腺炎组(P<0.001)。结论胰腺癌患者体内VitE量显著减少,提示胰腺癌变可能与体内氧化/抗氧化系统失衡有关。

关 键 词:维生素E  胰腺病  胰腺癌
文章编号:1000-2588(2002)03-0210-02
修稿时间:2001-07-18

Alteration of Vitamin E levels in patients with pancreatic adenocarcinoma
WANGDe-feng,QUXiao-ci,DAIZheng-qing AffiliatedHospitalof NantongMedicalCollege,Nantong,China. Alteration of Vitamin E levels in patients with pancreatic adenocarcinoma[J]. Journal of Southern Medical University, 2002, 22(3): 210-211
Authors:WANGDe-feng  QUXiao-ci  DAIZheng-qing AffiliatedHospitalof NantongMedicalCollege  Nantong  China
Affiliation:WANGDe-feng,QUXiao-ci,DAIZheng-qing AffiliatedHospitalof NantongMedicalCollege,Nantong226001,China
Abstract:Objective To investigatethealterationsof VitaminE(VitE)levelsinpatientswithpancreaticadenocarcinoma andexploreitsmechanismof action.Method A comparativeanalysisof theserumVitE levelswas conductedin patients withvariouspancreaticdiseases.Results In patientswithacutepancreatitis,chronicpancreatitisandpancreaticadenocar-cinoma,serumVitE levelsweresignificantlylowerthanthosein normalsubjects(P<0.05),andamongthe3groupsof patientswithpancreaticdiseases,patientswiththemalignancieshadsignificantlylowerVitE levelsthantheother2groupsof patients(P<0.001)Conclusion Significantreductionin VitE levelsoccursin patientswithpancreaticadenocarcinoma,indicatingthatoxidationand anti-oxidationimbalancemightbe involvedin the pathogenesisof the malignancyin the pancreas.
Keywords:vitaminE  pancreaticdiseases  pancreaticadenocarcinoma
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