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CT灌注参数BF、PS临界值对鼻咽癌放疗后复发的诊断性研究
引用本文:金观桥,苏丹柯,刘丽东,朱旭娜,谢东,赖少侣,黄向阳,李强.CT灌注参数BF、PS临界值对鼻咽癌放疗后复发的诊断性研究[J].临床放射学杂志,2011,30(2).
作者姓名:金观桥  苏丹柯  刘丽东  朱旭娜  谢东  赖少侣  黄向阳  李强
作者单位:广西医科大学附属肿瘤医院影像中心,南宁,530021
摘    要:目的探讨CT灌注参数血流量(BF)、表面通透性(PS)临界值对鼻咽癌(nasopharyngeal carcinoma,NPC)放疗后局部复发诊断的准确性。资料与方法回顾性分析150例NPC患者放疗后经CT灌注扫描资料,利用受试者工作特征(ROC)曲线分析BF、PS值对诊断NPC放疗后局部复发最佳临界值,计算BF、PS值临界值对诊断局部复发的预测值以及似然比(LR)。结果 CT灌注参数BF、PS临界值诊断NPC放疗后局部复发阳性预测值、阴性预测值分别为90.9%、89.2%和76.4%、70.1%;BF、PS临界值的阳性结果的LR分别为4.7和5,BF、PS阴性结果的LR分别为0.14和0.02。结论 CT灌注成像参数BF、PS临界值对诊断NPC放疗后局部复发具有较好预测值,并具有较好的LR,有助于NPC放疗后局部复发诊断。

关 键 词:复发性鼻咽癌  体层摄影术  X线计算机  似然比  

Likelihood Ratio of Diagnosing Recurrent NPC with Radiation Therapy by Cutoff Value of CT Perfusion Parameters
JIN Guanqiao,SU Danke,LIU Lidong,et al..Likelihood Ratio of Diagnosing Recurrent NPC with Radiation Therapy by Cutoff Value of CT Perfusion Parameters[J].Journal of Clinical Radiology,2011,30(2).
Authors:JIN Guanqiao  SU Danke  LIU Lidong  
Institution:JIN Guanqiao,SU Danke,LIU Lidong,et al.Image Center,the Affiliated Tumor Hospital of Guangxi Medical University,Nanning,Guangxi Zhuang Autonomour Region 530021,P.R.China
Abstract:Objective To explore the diagnostic accuracy of cutoff value of CT perfusion parameters(BF and PS) in detecting recurrent nasopharyngeal carcinoma (NPC) with radiation therapy.Materials and Methods CT perfusion data of 150 NPC patients with radiation therapy were retrospectively analyzed,Cutoff value in blood flow (BF) and permeability surface(PS)were achieved for diagnosis of recurrent NPC with receiver operator characteristic curves.Predictive value(PV)and likelihood ratio(LR)of BF,PS cut off value were c...
Keywords:Recurrent nasopharyngeal carcinoma Tomograph  X-ray computed Likelihood ratio  
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