补肾调周法合二藤汤灌肠治疗慢性盆腔炎性不孕症的临床疗效观察

目的观察补肾调周法口服中药合二藤汤保留灌肠法治疗慢性盆腔炎性不孕症疗效,评价其有效性和安全性。方法选取2016年2月—2017年1月期间山东省济宁市中医院妇产科门诊收治的60例慢性盆腔炎性不孕症患者,按随机数字表法分为治疗组和对照组,每组30例。对照组给予二藤汤,1剂/d,水煎400 ml,200 ml口服、200 ml保留灌肠。治疗组给予补肾调周方药口服1剂/d结合二藤汤灌肠2日1剂。两组均在每个月经周期的非经期期间治疗15 d,连续治疗3个月经周期为1个疗程。治疗结束后观察这两组患者妊娠情况、临床症状、体征评分、月经改善情况。结果治疗后治疗组患者受孕率66.67%(20/30),对照组受孕率46.33%(13/30),两组比较差异有统计学意义(P<0.05)。两组患者治疗后临床症状、体征积分均降低与治疗前比较差异有统计学意义(P<0.05),且治疗组临床症状、体征积分均优于对照组,两组比较差异有统计学意义(P<0.05)。治疗后治疗组总有效率90.00%(27/30),对照组总有效率73.33%(22/30),两组比较差异有统计学意义(P<0.05)。治疗后治疗组治疗盆腔炎症总有效率93.33%(28/30),对照组治疗盆腔炎症总有效率86.67%(26/30),两组比较差异有统计学意义(P<0.05)。结论补肾调周法口服中药合二藤汤灌肠治疗慢性盆腔炎性不孕症不但能提高妊娠率,而且还明显改善患者临床症状、体征、月经情况,疗效确切有效,在临床上值得推广应用。

Clinical Observation on the Treatment of Chronic Pelvic Inflammatory Infertility by Tonifying the Kidney and Regulating the Menstrual Cycle and Erteng Decoction Enema

Objective To observe the curative effect of the method of tonifying kidney and regulating the blood circulation on the treatment of chronic pelvic inflammatory infertility by Retention Enema with traditional Chinese medicine and Erteng Decoction.Methods From February 2016 to January 2017,60 patients with chronic pelvic inflammatory infertility who were admitted to the Obstetrics and Gynecology Department of Jining Hospital of Traditional Chinese Medicine in Shandong Province were selected and divided into treatment group and control group according to the random number table method,each group 30 cases.The control group was given Erteng Decoction 1 dose/d decoction 400 ml,200 ml orally,and200 ml retention enema.The treatment group was given 1 dose of Bushen Tiaozhou Recipe orally combined with Erteng Decoction enema on 2 days.Both groups were treated for 15 days during the non-menstrual period of each menstrual cycle,and 3 consecutive menstrual cycles constituted a course of treatment.After the treatment,the pregnancy status,clinical symptoms,physical sign scores,and menstrual improvement of these two groups were observed.Results After treatment,the pregnancy rate of the treatment group was 66.67%(20/30),and the pregnancy rate of the control group was 46.33%(13/30).The difference between the two groups was statistically significant(P<0.05).The clinical symptoms and signs scores of the two groups of patients decreased after treatment and the difference was statistically significant(P<0.05),and the clinical symptoms and signs scores of the treatment group were better than those of the control group.The difference between the two groups was statistically significant(P<0.05).After treatment,the total effective rate of the treatment group was 90.00%(27/30),and the total effective rate of the control group was 73.33%(22/30).The difference between the two groups was statistically significant(P<0.05).After treatment,the total effective rate of treating pelvic inflammation in the treatment group was 93.33%(28/30),and the total effective rate of treating pelvic inflammation in the control group was 86.67%(26/30).The difference between the two groups was statistically significant(P<0.05).Conclusion The treatment of chronic pelvic inflammatory infertility with the method of invigorating the kidney and regulating the menstruation,combined with Erteng decoction,can not only increase the pregnancy rate,but also significantly improve the clinical symptoms,signs,and menstrual conditions of patients.The curative effect is definite and effective.It is worthy of clinical application.