| 纳米硒抗菌的研究进展及其应用 |
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| 引用本文： | 杨超群,陈璨羽,木拜西尔&#;麦麦提依明,刘静,邓国英. 纳米硒抗菌的研究进展及其应用[J]. 中国感染控制杂志, 2022, 21(7): 718-722. DOI: 10.12138/j.issn.1671-9638.20221820 |
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| 作者姓名： | 杨超群,陈璨羽,木拜西尔&# 麦麦提依明,刘静,邓国英 |
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| 作者单位： | 1. 上海市第一人民医院创伤中心, 上海 201620;2. 上海交通大学基础医学院, 上海 200025;3. 上海交通大学材料学院, 上海 200240 |
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| 摘 要： | 医院内获得性感染和多重耐药菌的问题持续存在,但抗菌药物的作用逐渐弱化。在诸多新型抗菌药物中,纳米硒相对低毒性,具有较强抗菌效能。因此,本文从纳米硒的抗菌活性及其影响因素、抗菌机制、改良纳米硒材料的研究进展三个方面对纳米硒材料进行综述,并对纳米硒的临床应用进行阐述与展望,以期为其在抗菌领域的研究与应用提供参考。
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| 关 键 词： | 纳米硒 抗菌机制 抗菌活性 临床应用 |
| 收稿时间： | 2021-08-27 |
Advance and application of antimicrobial efficacy of nano-selenium |
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| Chao-qun YANG,Can-yu CHEN,MUBAIXIER,#;Maimaitiyiming,Jing LIU,Guo-ying DENG. Advance and application of antimicrobial efficacy of nano-selenium[J]. Chinese Journal of Infection Control, 2022, 21(7): 718-722. DOI: 10.12138/j.issn.1671-9638.20221820 |
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| Authors: | Chao-qun YANG,Can-yu CHEN,MUBAIXIER&# Maimaitiyiming,Jing LIU,Guo-ying DENG |
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| Affiliation: | 1. Trauma Center, Shanghai General Hospital, Shanghai 201620, China;2. Shanghai Jiao Tong University College of Basic Medical Sciences, Shanghai 200025, China;3. School of of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China |
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| Abstract: | The problem of healthcare-assocaited infection (HAI) and multidrug-resistant organism persists, but the role of antimicrobial agents is gradually weakened. Among many new antimicrobial agents, nano-selenium has relatively low toxicity and strong antimicrobial efficacy. Therefore, this paper introduces nano-selenium materials from three aspects: antimicrobial activity and its influencing factors, antimicrobial mechanism, and research progress of improved nano-selenium materials, elaborating and looking forward to the clinical application of nano-sele-nium, so as to provide reference for its research and application in antimicrobial field. |
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| Keywords: | nano-selenium antimicrobial mechanism antimicrobial activity clinical application |
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