中医辨证分型论治多囊卵巢综合征的疗效及其影响因素分析

目的 探讨中医辨证分型论治多囊卵巢综合征(PCOS)的疗效,并分析影响PCOS的相关因素.方法 选取2017年5月—2019年5月就诊的PCOS患者198例,其中西药组50例,采用炔雌醇环丙孕酮片(达英-35)进行治疗,中医辨证分型组148例,其中肾亏血瘀型55例,痰凝肾虚型54例,肝火郁热型39例.各证型在西药组治疗...

Efficacy of TCM Syndrome Differentiation Treatment in treating Polycystic Ovary Syndrome and Analysis of Influencing Factors

Objective To investigate the efficacy of traditional chinese medicine(TCM)syndrome differentiation in the treatment of polycystic ovary syndrome(PCOS),and to analyze the influencing factors of PCOS.Methods A total of 198 PCOS patients in our hospital from May 2017 to May 2019 were selected as the observation group.Among them,50 patients in the western medicine group were treated with ethinyl estradiol and cyproterone tablets(Diane-35).There were 148 cases of TCM syndrome differentiation,55 cases of kidney deficiency and blood stasis,54 cases of phlegm and kidney deficiency,and 39 cases of liver-fire-stagnation-heat type.On the basis of western medicine group treatment,each syndrome group adopts TCM syndrome differentiation treatment.During the same period,150 healthy women of childbearing age were selected as the control group.The effect of the observation group after treatment and the changes in sex hormone levels before and after treatment were compared.Single factor analysis and multiple logistic regression model were used to analyze the factors affecting PCOS.Results After treatment,the overall effective rate of kidney deficiency and blood stasis type,phlegm coagulation and kidney deficiency type,and liver-fire stagnation-heat type were all higher than those of the western medicine group(P<0.05).After treatment,the testosterone(TSHO),luteinizing hormone(LH),follicle stimulating hormone(FSH)and LH/FSH values of each syndrome group and western medicine group were lower than before treatment,and estradiol(E2)levels were higher than treatment Before,and the levels of sex hormones in each syndrome group were better than those in the western medicine group(P<0.05).Univariate analysis showed that whether the body mass index is normal,lack of exercise,excessive psychological pressure,regular work and rest,with or without underlying diseases,and with or without a genetic history of PCOS are all related factors that affect the patient′s PCOS(P<0.05).Multivariate logistic analysis showed that whether the body mass index is normal,lack of exercise,excessive psychological stress,combined with underlying diseases,and whether there is a genetic history of PCOS are all independent factors affecting PCOS.Conclusion TCM treatment of PCOS has significant effect on regulating the levels of sex hormones.Maintaining scientific and reasonable life habit and regulate psychological mood is helpful to reduce the risk of PCOS.