甘草酸的文献计量学分析与可视化

目的] 使用文献可视化分析程序CiteSpace对近20年Web of Science数据库中甘草酸的相关文献进行可视化分析，得到显示该领域研究情况的知识图谱。方法] 以Glycyrrhizic acid、Glycyrrhizin acid、Glycyrrhiza acid、Glycyrrhizinate和Glycyrrhizic为主题分别检索2000—2020年期间Web of Science数据库中甘草酸相关的研究性论文及综述。检索结果去重后以CiteSpace程序分析其关键词共现和聚类、国家、研究领域、发表期刊、共被引用论文等情况，并利用程序将分析结果可视化。结果] 通过检索获得2 418篇文献，发表文章数量较多的国家是中国（1 057篇），日本（281篇）和韩国（186篇），其中有537篇受到国家自然科学基金资助，占总数的22.21%。共现关键词包括保肝、抗炎、抗氧化应激等研究方向，主要发表在Molecules、Biological Pharmaceutical Bulletin、Journal of Ethnopharmacology等期刊。结论] CiteSpace的分析结果展现了甘草酸在药理学、化学、食品营养学等领域自21世纪以来的文献发表情况、研究方向、热点关键词等，并将其可视化为知识图谱，精准定位知识前沿，为未来关于甘草酸的研究选题提供一定参考。

A bibliometric analysis and visualization of glycyrrhizic acid

Objective] CiteSpace was used to analyze the articles of glycyrrhizic acid in the Web of Science database published in the latest two decades,and the knowledge map showing the research situation in this field was obtained.Methods] Glycyrrhizic acid,glycyrrhizin acid,glycyrrhiza acid,glycyrrhizinate and glycyrrhizic were used as theme to search the articles in Web of Science database within the time range of 2000 to 2020 for research papers and reviews relevant to glycyrrhizic acid. After de-duplication,CiteSpace was used to analyze the co-occurrence and clustering of keywords,countries,research fields,journals,cited papers,and the analysis results were visualized by the program.Results] Among the 2 418 articles,China (1 057),Japan (281) and South Korea (186) published the most,537 of which were funded by NSFC,accounting for 22.21% of the total. The co-occurrence keywords include liver protection,anti-inflammation and anti-oxidative stress. The articles are mainly published in journals such as Molecules,Biological Pharmaceutical Bulletin,and Journal of Ethnopharmacology.Conclusion] The analysis results show the publication situation,research direction,and hot keywords of glycyrrhizic acid in the fields of pharmacology,chemistry and food nutrition since the 21st century. Besides,the visualization and accurate location of knowledge frontier will provide some reference for the future research of glycyrrhizic acid.