|
|||||
|
|
Fludarabine-associated autoimmune hemolytic anemia occurring in B-cell chronic lymphocytic leukemia |
|
| Authors: | Nishida Hiroko Murase Tadashi Ueno Hironori Park Jae Wong Yano Takahiro Ikeda Yasuo |
| Affiliation: | aDivision of Hematology, Department of Internal Medicine, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan bDivision of Hematology, Department of Internal Medicine, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan cDepartment of Internal medicine, Fuji Xerox Health Promotion Center, Tokyo, Japan |
| Abstract: | Autoimmune phenomena are reported to occur frequently in B-cell chronic leukemia (B-CLL). Fludarabine, one of the most effective chemotherapeutic agents for CLL, may increase the risk of these phenomena and may be life-threatening. Here we present a case of an 80-year-old man with B-CLL who developed autoimmune hemolytic anemia (AIHA), associated with one cycle of fludarabine treatment, and who was successfully treated with rituximab and prednisolone. |
| Keywords: | B-CLL Fludarabine AIHA Rituximab Prednisolone |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |